
Immunization is one of the most effective measures of public health medicine, saving countless lives and preventing lifelong disabilities. Close vaccine safety-surveillance is currently underway for these new vaccines. Due to the SARS-CoV2 pandemic, new types of vaccines have been developed and are now available. The only confirmed associations, although very rare, are those between the flu vaccine and Guillain-Barré syndrome, especially with old vaccine preparations, and measles-mumps-rubella (MMR) vaccine and thrombocytopenia. Furthermore, epidemiological studies do not support the hypothesis that vaccines cause systemic autoimmune diseases. Currently, no mechanisms have been demonstrated that could explain the correlation between vaccination and the development of autoimmune diseases. Among the adverse reactions to vaccines, one of the most feared is the triggering of autoimmune diseases, which are a heterogeneous group of disorders characterized by dysregulation of the immune system. An adverse event following immunization (AEFI) may be a true adverse reaction caused by the vaccine or an event that temporally occurred after immunization but is not caused by it. Vaccines are extremely safe, however, no vaccine is completely free from risks and adverse events can occur following vaccination. Vaccines represent one of the most effective measures of public health medicine, saving countless lives and preventing lifelong disabilities.
